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The opposable thumb you use to hold a pencil was long thought to be a defining aspect of humans. But an analysis of finger bones suggests stone tool use by pre-humans — perhaps 3 million years ago.

President Obama and Mitt Romney are scheduled to address the National Association of Latino Elected and Appointed Officials conference in Orlando. Robert Siegel speaks with Arturo Vargas, executive director of the group, about what issues attendees would like to hear about.

Thirteen years after a study on hormone therapy was abruptly halted due to concerns about cancer risk, some doctors say that it's safe for most younger women if they take hormones short term.

Diego Roman Elena Rodriguez's brother was unarmed, walking on a sidewalk in Nogales, when Lonnie Swartz shot him. The agent says he felt threatened by rock-throwers; he's expected to plead not guilty.

James Comey said police restraint, born from increased scrutiny in the wake of high-profile police killings, may be contributing to an uptick in violent crimes in some cities.

Even though he wasn't on the stage at the second-tier debate, the four candidates didn't shy away from taking on Donald Trump. The candidates also discussed immigration and national security.

There's a lot at stake for Carly Fiorina at tonight's Republican debate. She joins 10 men on stage, including Donald Trump, who was recently quoted making negative comments about her face.

Steve Inskeep talks to film critic Kenneth Turan about some of the movies we should watch for coming out of this year's Sundance Film Festival in Park City, Utah.

A report from doctors in Argentina raises the possibility that a mosquito pesticide could be responsible for an increase in microcephaly in Brazil. But many top scientists strongly disagree.

The Japanese Christmas cake takes its name from the Christian holiday, but it actually symbolizes building a life of prosperity from nothing. And it's ubiquitous (it's even in your smartphone).